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Article

Intronic polymorphisms of cytochromes P450.

Human genomics - 1 Aug 2010

Ingelman-Sundberg Magnus, Sim Sarah C

Abstract excerpt

The cytochrome P450 enzymes active in drug metabolism are highly polymorphic. Most allelic variants have been described for enzymes encoded by the cytochrome P450 family 2 (CYP2) gene family, which has 252 different alleles. The intronic polymorphisms in the cytochrome P450 genes account for only a small number of the important variant alleles; however, the most important ones are CYP2D6*4 and CYP2D6*41 , which...

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Identifiers

PMID: 20846929
DOI: 10.1186/1479-7364-4-6-402
PMCID: PMC3525217

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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