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Article

Effects of FGFR4 G388R, V10I polymorphisms on the likelihood of cancer.

Scientific reports - 14 Jan 2021

Peng Tao, Sun Yangyang, Lv Zhiwei, Zhang Ze, Su Quanxin, Wu Hao, Zhang Wei, Yuan Wei, Zuo Li, Shi Li, Zhang Li-Feng, Zhou Xiaoli, Mi Yuanyuan

Abstract excerpt

The correlation between G388R or V10I polymorphisms of fibroblast growth factor receptor (FGFR) 4 gene and the risk of carcinoma has been investigated previously, but the results are contradictory. Odds ratios (ORs) with 95% confidence intervals (95%CIs), in silico tools, and immunohistochemical staining (IHS) were adopted to assess the association. In total, 13,793 cancer patients and 16,179 controls were...

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Identifiers

PMID: 33446698
DOI: 10.1038/s41598-020-80146-y
PMCID: PMC7809464

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