Article
FGFR4 Arg388 Is Correlated with Poor Survival in Resected Colon Cancer Promoting Epithelial to Mesenchymal Transition.
Cancer research and treatment - 1 Jul 2017
Cho Sang Hee, Hong Chang Soo, Kim Hee Nam, Shin Min Ho, Kim Ka Rham, Shim Hyun Jeong, Hwang Jun Eul, Bae Woo Kyun, Chung Ik Joo
Abstract excerpt
PURPOSE: Fibroblast growth factor receptor 4 (FGFR4) plays an important role in cancer progression during tumor proliferation, invasion, and metastasis. This study evaluated the prognostic role of FGFR4 polymorphism in patients with resected colon cancer, including the underlying mechanism. MATERIALS AND METHODS: FGFR4 polymorphism was characterized in patientswho received curative resection for stage III colon...
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