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Article

FGFR4 Gly388Arg Polymorphism Affects the Progression of Gastric Cancer by Activating STAT3 Pathway to Induce Epithelial to Mesenchymal Transition.

Cancer research and treatment - 1 Oct 2020

Ye Yanwei, Li Jie, Jiang Dongbao, Li Jingjing, Xiao Chuangfeng, Li Yingze, Han Chao, Zhao Chunlin

Abstract excerpt

PURPOSE: Fibroblast growth factor receptor 4 (FGFR4) plays a critical role in cancer progression involving in tumor proliferation, invasion, and metastasis. This study clarified the role of FGFR4-Arg388 variant in gastric cancer (GC), and more importantly highlighted the possibility of this single nucleotide polymorphism (SNP) as potential therapeutic targets. MATERIALS AND METHODS: FGFR4 polymorphism was...

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Identifiers

PMID: 32599983
DOI: 10.4143/crt.2020.138
PMCID: PMC7577822

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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