Article
Directionality of point mutation and 5-methylcytosine deamination rates in the chimpanzee genome.
BMC genomics - 13 Dec 2006
Jiang Cizhong, Zhao Zhongming
Abstract excerpt
BACKGROUND: The pattern of point mutation is important for studying mutational mechanisms, genome evolution, and diseases. Previous studies of mutation direction were largely based on substitution data from a limited number of loci. To date, there is no genome-wide analysis of mutation direction or methylation-dependent transition rates in the chimpanzee or its categorized genomic regions. RESULTS: In this study,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.