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Article

Variants in folate pathway genes as modulators of genetic instability and lung cancer risk.

Genes, chromosomes & cancer - 1 Jan 2011

Piskac-Collier Amanda L, Monroy Claudia, Lopez Mirtha S, Cortes Andrea, Etzel Carol J, Greisinger Anthony J, Spitz Margaret R, El-Zein Randa A

Abstract excerpt

Genetic instability plays a crucial role in cancer development. The genetic stability of the cell as well as DNA methylation status could be modulated by folate levels. Several studies suggested associations between polymorphisms in folate genes and alterations in protein expression and variations in serum levels of the folate. The objective of this study was to investigate the effect of folate pathway...

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Source

Identifiers

PMID: 20842733
DOI: 10.1002/gcc.20826

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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