Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of common polymorphisms in folate uptake and metabolism genes on frequency of micronucleated lymphocytes in a South Australian cohort.

Mutation research - 1 Jun 2009

Dhillon Varinderpal, Thomas Philip, Fenech Michael

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in genes that control folate uptake and metabolism may have an important effect on chromosomal stability. The present study investigated the effect of common SNPs in some of these critical genes on frequency of lymphocytes with micronuclei, a biomarker of chromosome breakage or loss. 164 individuals (94 males and 70 females) of different age ranging from 18 to 73 years...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
Share to Biological Transport, Active

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Folic Acid

Share to Lymphocytes

Share to Micronuclei, Chromosome-Defective

Share to Micronucleus Tests

Share to Reduced Folate Carrier Protein

Share to South Australia

Source

Identifiers

PMID: 19427504
DOI: 10.1016/j.mrfmmm.2009.02.007

Genes

MTR
MTHFR
MTRR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of common polymorphisms in folate uptake and metabolism genes on frequency of micronucleated lymphocytes in a South Australian cohort.PMID 19427504Read ↗

Methylenetetrahydrofolate reductase, common polymorphisms, and relation to disease.Semantic proximity Read ↗

Genetic polymorphisms in folate and homocysteine metabolism as risk factors for DNA damageSemantic proximity Read ↗

Importance of gene variants and co-factors of folate metabolic pathway in the etiology of idiopathic intellectual disability.Semantic proximity Read ↗

Folate status, metabolic genotype, and biomarkers of genotoxicity in healthy subjects.Semantic proximity Read ↗

Effect of dietary intervention on human micronucleus frequency in lymphocytes and buccal cellsSemantic proximity Read ↗

Variants in folate pathway genes as modulators of genetic instability and lung cancer risk.Semantic proximity Read ↗

A decreased micronucleus frequency in human lymphocytes after folate and vitamin B12 intervention: a preliminary study in a Yunnan population.Semantic proximity Read ↗

Mechanisms of genome instability from cellular folate stressSemantic proximity Read ↗

Associations between single nucleotide polymorphisms in folate uptake and metabolizing genes with blood folate, homocysteine, and DNA uracil concentrations.Semantic proximity Read ↗

Genetic polymorphisms and micronucleus formation: a review of the literature.Semantic proximity Read ↗

A polymorphism of the methionine synthase reductase gene increases chromosomal damage in peripheral lymphocytes in smokers.Semantic proximity Read ↗

The Frequency of the 677C>T and 1298A>C Polymorphisms in the Methylenetetrahydrofolate Reductase (MTHFR) Gene in the Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.