Article
The Role of Micronucleus Assay to Detect Genetic Instability in Respiratory Cancer Patients.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 2019
Bolognesi Claudia, Bruzzone Marco, Fontana Vincenzo, Ugolini Donatella, Compalati Andrea, Stagnaro Laura, Ceppi Marcello
Abstract excerpt
Asbestos represents the main risk factor for malignant pleural mesothelioma (PM) even if only a minority of exposed people develop this tumor, suggesting a significant role for genetic susceptibility. This study aims to evaluate micronuclei (MN) frequency as a biomarker of genome instability in peripheral blood lymphocytes of PM and lung cancer (LC) patients when compared with healthy controls (HCs) and patients...
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