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Article

Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

Molecular carcinogenesis - 1 Oct 2012

Buch Shama C, Diergaarde Brenda, Nukui Tomoko, Day Roger S, Siegfried Jill M, Romkes Marjorie, Weissfeld Joel L

Abstract excerpt

DNA repair and cell cycle control play an important role in the repair of DNA damage caused by cigarette smoking. Given this role, functionally relevant single nucleotide polymorphisms (SNPs) in genes in these pathways may well affect the risk of smoking-related lung cancer. We examined the relationship between 240 SNPs in DNA repair and cell cycle control pathway genes and lung cancer risk in a case-control...

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Source

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Identifiers

PMID: 21976407
DOI: 10.1002/mc.20858
PMCID: PMC3289753

Genes

LIG1
PARP1
XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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