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Article

Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish.

Molecular biology reports - 1 Mar 2011

Long Yong, Li Qing, Cui Zongbin

Abstract excerpt

ABCC1/MRP1 belongs to the ATP-binding cassette superfamily and its elevated expression is closely associated with the multidrug resistance of various tumor cells. In normal tissues, ABCC1 confers resistance to a wide variety of xenobiotics and toxicants, demonstrating its important roles in tissue defense. Here, we report the cloning and functional characterization of abcc1 gene in zebrafish. This gene is...

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Share to Embryo, Nonmammalian
Share to Gene Expression Regulation, Developmental
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Multidrug Resistance-Associated Proteins

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Source

Identifiers

PMID: 20842442
DOI: 10.1007/s11033-010-0283-z

Genes

ABCC1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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