Article

Characterization and tissue localization of zebrafish homologs of the human <i>ABCB1</i> multidrug transporter

2021-02-18

Abstract excerpt

<h4>ABSTRACT</h4> Given its similarities with mammalian systems, the zebrafish has emerged as a potential model to study the blood-brain barrier (BBB). Capillary endothelial cells at the human BBB express high levels of P-glycoprotein (P-gp, encoded by the ABCB1 gene) and ABCG2 (encoded by the ABCG2 gene). However, little information has been available about ATP-binding cassette transporters expressed at the ze...

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Literature Corpus work: 90d5c1e5-9f0c-5c8b-8cf5-2a4cc05c5b2b
DOI: 10.1101/2021.02.18.431829

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