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ABC transporters in fish species: a review

22 Jul 2014

Abstract excerpt

ATP-binding cassette (ABC) proteins were first recognized for their role in multidrug resistance (MDR) in chemotherapeutic treatments, which is a major impediment for the successful treatment of many forms of malignant tumors in humans. These proteins, highly conserved throughout vertebrate species, were later related to cellular detoxification and accounted as responsible for protecting aquatic organisms from...

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PMID: 25101003
DOI: 10.3389/fphys.2014.00266

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