Sirtuins: Common Targets in Aging and in Neurodegeneration

Abstract excerpt

Aging has been a subject of interest since primordial times. More recently, it became clear that aging is the major known risk factor for several neurodegenerative disorders, such as Alzheimers disease, Parkinsons disease and Huntingtons disease. A major focus in the field of aging is to examine whether the genetic regulators of lifespan also regulate the trigger and/or progression of age-related disorders....

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