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Sirtuins and their Biological Relevance in Aging and Age-Related Diseases

1 Jan 2020

Abstract excerpt

Sirtuins, initially described as histone deacetylases and gene silencers in yeast, are now known to have many more functions and to be much more abundant in living organisms. The increasing evidence of sirtuins in the field of ageing and age-related diseases indicates that they may provide novel targets for treating diseases associated with aging and perhaps extend human lifespan. Here, we summarize some of the...

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PMID: 32765955
DOI: 10.14336/ad.2019.0820

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