Article
Influence of RET/PTC1 and RET/PTC3 oncoproteins in radiation-induced papillary thyroid carcinomas on amounts of cytoskeletal protein species.
Amino acids - 1 Jul 2011
Zeindl-Eberhart Evelyn, Liebmann Sibylle, Jungblut Peter Roman, Mattow Jens, Schmid Monika, Kerler Rosi, Rabes Hartmut Manfred
Abstract excerpt
Radiation-induced human papillary thyroid carcinomas (PTCs) show a high prevalence of fusions of the RET proto-oncogene to heterologous genes H4 (RET/PTC1) and ELE1 (RET/PTC3), respectively. In contrast to the normal membrane-bound RET protein, aberrant RET fusion proteins are constitutively acti...
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