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Article

Influence of RET/PTC1 and RET/PTC3 oncoproteins in radiation-induced papillary thyroid carcinomas on amounts of cytoskeletal protein species.

Amino acids - 1 Jul 2011

Zeindl-Eberhart Evelyn, Liebmann Sibylle, Jungblut Peter Roman, Mattow Jens, Schmid Monika, Kerler Rosi, Rabes Hartmut Manfred

Abstract excerpt

Radiation-induced human papillary thyroid carcinomas (PTCs) show a high prevalence of fusions of the RET proto-oncogene to heterologous genes H4 (RET/PTC1) and ELE1 (RET/PTC3), respectively. In contrast to the normal membrane-bound RET protein, aberrant RET fusion proteins are constitutively active oncogenic cytosolic proteins that can lead to malignant transformation of thyroid epithelia. To detect specific...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Proto-Oncogene Mas

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Share to Thyroid Cancer, Papillary

Source

Identifiers

PMID: 20839015
DOI: 10.1007/s00726-010-0733-x

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Influence of RET/PTC1 and RET/PTC3 oncoproteins in radiation-induced papillary thyroid carcinomas on amounts of cytoskeletal protein species.PMID 20839015Read ↗

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