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Article

RET/PTC Translocations and Clinico-Pathological Features in Human Papillary Thyroid Carcinoma

1 Jan 2012

Abstract excerpt

Thyroid carcinoma is the most frequent endocrine cancer accounting for 5-10% of thyroid nodules. Papillary histotype (PTC) is the most prevalent form accounting for 80% of all thyroid carcinoma. Although much is known about its epidemiology, pathogenesis, clinical, and biological behavior, the only documented risk factor for PTC is the ionizing radiation exposure. Rearrangements of the Rearranged during...

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PMID: 22654872
DOI: 10.3389/fendo.2012.00054

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