Article
Expression of wild-type ret, ret/PTC and ret/PTC variants in papillary thyroid carcinoma in Germany.
Langenbeck's archives of surgery - 1 Feb 1999
Mayr B, Pötter E, Goretzki P, Rüschoff J, Dietmaier W, Hoang-Vu C, Dralle H, Brabant G
Abstract excerpt
INTRODUCTION: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. Although the clinical course is usually rather benign, a subset of tumors is more aggressive. The ret/PTC oncogene was found only in PTC, with varying frequencies of up to 30%. Recently, two new variants of ret/PTC could be identified in post-Chernobyl PTCs, which raised the possibility that the prevalence of ret/PTC in...
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