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Article

Gene expression in RET/PTC3 and E7 transgenic mouse thyroids: RET/PTC3 but not E7 tumors are partial and transient models of human papillary thyroid cancers.

Endocrinology - 1 Oct 2008

Burniat Agnès, Jin Ling, Detours Vincent, Driessens Natacha, Goffard Jean-Christophe, Santoro Massimo, Rothstein Jay, Dumont Jacques E, Miot Françoise, Corvilain Bernard

Abstract excerpt

We studied gene expression profiles in two mouse models of human thyroid carcinoma: the Tg-RET/PTC3 (RP3) and Tg-E7 mice. RP3 fusion gene is the most frequent mutation found in the first wave post-Chernobyl papillary thyroid cancers (PTCs). E7 is an oncoprotein derived from the human papillomavir...

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Share to Carcinoma, Papillary
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neovascularization, Pathologic

Share to Oncogene Proteins, Viral

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Share to Proto-Oncogene Proteins c-ret

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Source

Identifiers

PMID: 18583418
DOI: 10.1210/en.2008-0531

Genes

RET
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18583418-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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