Article
Tau haplotypes and ApoE4 do not act in synergy on Alzheimer's disease.
Psychiatry research - 30 Apr 2011
Almos Péter Z, Horváth Szatmár, Czibula Agnes, Raskó István, Domján Nóra, Juhász Anna, Janka Zoltán, Kálmán János
Abstract excerpt
There are conflicting results regarding the role of tau (MAPT) haplotypes in neurodegenerative disorders. Recent reports suggest that ethnicity factors and gene-gene interactions may influence the risk of developing Alzheimer's disease (AD). The present study investigates possible synergism between MAPT haplotype and ApoE state in Hungarian Caucasian AD cases (n=91) and control (n=83) population. The difference...
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