Article
Association between H2 haplotype of microtubule associated protein tau gene (deletion / insertion) with Alzheimer Disease in Tunisian patients.
Neurological research - 1 Sept 2022
Fray Saloua, Achouri-Rassas Afef Achouri, Hadj Fredj Sondes, Messaoud Taieb, Belal Samir
Abstract excerpt
It is widely recognized that Alzheimer's disease (AD) is the main cause of dementia in the elderly. AD is typically characterized by the extraneuronal plaque made up essentially of the amyloid β peptide and intraneuronal tangles of hyperphosphorylated microtubule-associated Tau protein. This study investigates the possible interaction between AD and the deletion/insertion polymorphism in intron 9 of the Tau gene...
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