Article
Ubiquitin-dependent and ubiquitin-independent control of subunit stoichiometry in the SWI/SNF complex.
The Journal of biological chemistry - 12 Nov 2010
Keppler Brian R, Archer Trevor K
Abstract excerpt
The mammalian SWI/SNF chromatin remodeling complex is a key player in multiple chromatin transactions. Core subunits of this complex, including the ATPase, Brg-1, and various Brg-1-associated factors (BAFs), work in concert to maintain a functional remodeling complex. This intra-complex regulatio...
Topics
- Amino Acid Substitution
- Blotting, Western
- Carrier Proteins
- Cell Line, Tumor
- Chromosomal Proteins, Non-Histone
- DNA-Binding Proteins
- Humans
- Immunoprecipitation
- Mutation
- Proteasome Endopeptidase Complex
- Protein Binding
- Protein Subunits
- RNA Interference
- Transcription Factors
- Transfection
- Ubiquitin
- Ubiquitin-Protein Ligases
- Ubiquitination