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Article

Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes

20 Jan 1998

Abstract excerpt

The SWI/SNF complex in yeast and Drosophila is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. The mechanism by which it is targeted to specific genes is poorly understood and may involve direct DNA binding and/or interactions with specific or general transcription factors. We have previously purified a mammalian complex by using...

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Identifiers

PMID: 9435219
DOI: 10.1073/pnas.95.2.492

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Source receipt: pubmed, retrieved 7 Sept 2026.

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