Article
Development, phenotype, and function of non-conventional B cells.
Comparative immunology, microbiology and infectious diseases - 1 Oct 2017
Prieto J M B, Felippe M J B
Abstract excerpt
Three populations of B cells develop in fetal life: B1, B2 and marginal zone B cells. B1 cells play important roles in innate immunity in contrast to B2 cells that perform the conventional roles in adaptive immunity. B1 cells were first identified in mice based on their expression of CD5 and spontaneous secretion of IgM. B1 cells were subsequently found to have unique developmental, phenotype, tissue...
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