Article
EMR-3: a potential mediator of invasive phenotypic variation in glioblastoma and novel therapeutic target.
Neuroreport - 17 Nov 2010
Kane Ari J, Sughrue Michael E, Rutkowski Martin J, Phillips Joanna J, Parsa Andrew T
Abstract excerpt
Epidermal growth factor module-containing mucin-like hormone receptor-3 (EMR-3) is a G-protein coupled receptor with unknown ligand and cellular function. Upregulation of EMR-3 in glioblastoma (GBM) multiforme is associated with poor survival. We investigated the expression patterns and functional significance of EMR-3 in GBM using immunohistochemistry, western blot, reverse transcription PCR, and small...
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