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Article

Notch pathway regulates female germ cell meiosis progression and early oogenesis events in fetal mouse

7 Jan 2014

Abstract excerpt

A critical process of early oogenesis is the entry of mitotic oogonia into meiosis, a cell cycle switch regulated by a complex gene regulatory network. Although Notch pathway is involved in numerous important aspects of oogenesis in invertebrate species, whether it plays roles in early oogenesis events in mammals is unknown. Therefore, the rationale of the present study was to investigate the roles of Notch...

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PMID: 24398584
DOI: 10.4161/cc.27708

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