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Identification of regulatory elements required for Stra8 expression in fetal ovarian germ cells of the mouse

11 Feb 2021

Abstract excerpt

ABSTRACT In mice, the entry of germ cells into meiosis crucially depends on the expression of stimulated by retinoic acid gene 8 (Stra8). Stra8 is expressed specifically in pre-meiotic germ cells of females and males, at fetal and postnatal stages, respectively, but the mechanistic details of its spatiotemporal regulation are yet to be defined. In particular, there has been considerable debate regarding whether...

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PMID: 33574039
DOI: 10.1242/dev.194977

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