Article
Light-induced phase shifts in mice lacking mPER1 or mPER2.
Journal of biological rhythms - 1 Apr 2003
Bae Kiho, Weaver David R
Abstract excerpt
Three homologs of the Drosophila Period gene have been identified in mammals. In mice, these three genes (mPer1, mPer2, and mPer3) have distinct roles in the circadian clockwork. While products of mPer1 and mPer2 play important roles in the maintenance of circadian rhythmicity, mPer3 gene products are dispensable for rhythmicity. Several studies also implicate mPER1 and mPER2 in transduction of photic information...
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