Article
The Conserved Kinases CDK-1, GSK-3, KIN-19, and MBK-2 Promote OMA-1 Destruction to Regulate the Oocyte-to-Embryo Transition in C. elegans.
Current biology : CB - 10 Jan 2006
Shirayama Masaki, Soto Martha C, Ishidate Takao, Kim Soyoung, Nakamura Kuniaki, Bei Yanxia, van den Heuvel Sander, Mello Craig C
Abstract excerpt
BACKGROUND: At the onset of embryogenesis, key developmental regulators called determinants are activated asymmetrically to specify the body axes and tissue layers. In C. elegans, this process is regulated in part by a conserved family of CCCH-type zinc finger proteins that specify the fates of early embryonic cells. The asymmetric localization of these and other determinants is regulated in early embryos through...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.