Article
Sub1 globally regulates RNA polymerase II C-terminal domain phosphorylation.
Molecular and cellular biology - 1 Nov 2010
García Alicia, Rosonina Emanuel, Manley James L, Calvo Olga
Abstract excerpt
The transcriptional coactivator Sub1 has been implicated in several aspects of mRNA metabolism in yeast, such as activation of transcription, termination, and 3'-end formation. Here, we present evidence that Sub1 plays a significant role in controlling phosphorylation of the RNA polymerase II large subunit C-terminal domain (CTD). We show that SUB1 genetically interacts with the genes encoding all four known CTD...
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