Article
Identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y.
The Journal of cell biology - 6 Sept 2010
Wiedemann Sonja M, Mildner Silke N, Bönisch Clemens, Israel Lars, Maiser Andreas, Matheisl Sarah, Straub Tobias, Merkl Rainer, Leonhardt Heinrich, Kremmer Elisabeth, Schermelleh Lothar, Hake Sandra B
Abstract excerpt
Nucleosomal incorporation of specialized histone variants is an important mechanism to generate different functional chromatin states. Here, we describe the identification and characterization of two novel primate-specific histone H3 variants, H3.X and H3.Y. Their messenger RNAs are found in certain human cell lines, in addition to several normal and malignant human tissues. In keeping with their primate...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.