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Article

Association of CYP19 and ESR1 pleiotropic genes with human longevity.

The journals of gerontology. Series A, Biological sciences and medical sciences - 1 Jan 2011

Corbo Rosa Maria, Ulizzi Laura, Positano Lidia, Scacchi Renato

Abstract excerpt

Aromatase (CYP19) and estrogen receptor-alpha (ESR1) are involved in the metabolism of estrogens, which have a relevant role in female and male aging. Moreover, due to their influence on fertility, both genes may be part of the longevity-fertility trade-off mechanism. This investigation examines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Genetic

Source

Identifiers

PMID: 20819792
DOI: 10.1093/gerona/glq160

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20819792-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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