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Article

Multilocus analyses of estrogen-related genes reveal involvement of the ESR1 gene in male infertility and the polygenic nature of the pathology.

Fertility and sterility - 1 Oct 2005

Galan Jose J, Buch Belen, Cruz Natalio, Segura Ana, Moron Francisco J, Bassas Lluis, Martinez-Pineiro Luis, Real Luis M, Ruiz Agustin

Abstract excerpt

OBJECTIVE: To examine whether polymorphisms within the ESR1, FSHR, ESR2, CYP19A1, and NRIP1 genes are susceptibility factors for human male idiopathic infertility and to test the joint effects of these genes on male reproductive function. DESIGN: Genetic association study of male infertility with...

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Source

Identifiers

PMID: 16213843
DOI: 10.1016/j.fertnstert.2005.03.070

Genes

ESR1
ESR2
FSHR
NRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16213843-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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