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Article

Association study of the oestrogen signalling pathway genes in relation to age at natural menopause.

Journal of genetics - 1 Dec 2007

He Li-Na, Xiong Dong-Hai, Liu Yong-Jun, Zhang Feng, Recker Robert R, Deng Hong-Wen

Abstract excerpt

Genetic factors play a significant role in influencing the variation of age at natural menopause (AANM). Estrogen receptor beta (ESR2), is an important factor in the mechanism of action of estrogen, while the aromatase gene (CYP19) and the 17-alpha-hydroxylase gene (CYP17) are involved in the biosynthesis of estrogen. We tested whether polymorphisms of ESR2, CYP19 and CYP17 genes are associated with AANM in...

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Source

Identifiers

PMID: 18305346
DOI: 10.1007/s12041-007-0034-7

Genes

ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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