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Article

Brain phenotype of carbonic anhydrase IX-deficient mice.

Transgenic research - 1 Feb 2012

Pan Pei-wen, Parkkila Anna-Kaisa, Autio Salla, Hilvo Mika, Sormunen Raija, Pastorekova Silvia, Pastorek Jaromir, Haapasalo Hannu, Parkkila Seppo

Abstract excerpt

Preliminary observations have suggested mild behavioral changes and a morphological disruption of brain histology in 1.5-year-old carbonic anhydrase IX (CA IX)-deficient (Car9 (-/-)) mice. These findings led us to design a 1-year follow-up study in which the behavior and brain histology of Car9 (-/-) and wild-type mice were monitored. Morphological analysis revealed vacuolar degenerative changes in the brains of...

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Identifiers

PMID: 21547424
DOI: 10.1007/s11248-011-9520-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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