Article
Membrane associated carbonic anhydrase IV (CA IV): a personal and historical perspective.
Sub-cellular biochemistry - 1 Jan 2014
Waheed Abdul, Sly William S
Abstract excerpt
Carbonic anhydrase IV is one of 12 active human isozymes and one of four expressed on the extracellular surfaces of certain endothelial and epithelial cells. It is unique in being attached to the plasma membrane by a glycosyl-phosphatiydyl-inositol (GPI) anchor rather than by a membrane-spanning domain. It is also uniquely resistant to high concentrations of sodium dodecyl sulfate (SDS), which allows purification...
Topics
- Animals
- Carbonic Anhydrase IV
- Catalysis
- Enzyme Stability
- Gene Expression Regulation, Enzymologic
- Humans
- Isoenzymes
- Mice
- Mutation
- Rats
- Structure-Activity Relationship
- Tissue Distribution
