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Polymorphic DNA repair and metabolic genes: a multigenic study on gastric cancer.

Mutagenesis - 1 Nov 2010

Palli Domenico, Polidoro Silvia, D'Errico Mariarosaria, Saieva Calogero, Guarrera Simonetta, Calcagnile Angelo S, Sera Francesco, Allione Alessandra, Gemma Simonetta, Zanna Ines, Filomena Alessandro, Testai Emanuela, Caini Saverio, Moretti Renato, Gomez-Miguel Maria-Jesus, Nesi Gabriella, Luzzi Ida, Ottini Laura, Masala Giovanna, Matullo Giuseppe, Dogliotti Eugenia

Abstract excerpt

Risk factors for gastric cancer (GC) include inter-individual variability in the inflammatory response to Helicobacter pylori infection, in the ability of detoxifying DNA reactive species and repairing DNA damage generated by oxidative stress and dietary carcinogens. To evaluate the association between polymorphic DNA repair genes and GC risk, a case-control study including 314 histologically confirmed GC...

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Source

Identifiers

PMID: 20817763
DOI: 10.1093/mutage/geq042

Genes

GSTT1
XPA
XPC
GSTM1
XRCC1
ERCC1
MGMT
OGG1
XRCC3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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