Article
Polymorphisms in genes involved in DNA repair and metabolism of xenobiotics in individual susceptibility to sporadic diffuse gastric cancer.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Ruzzo Annamaria, Canestrari Emanuele, Maltese Paolo, Pizzagalli Francesca, Graziano Francesco, Santini Daniele, Catalano Vincenzo, Ficarelli Rita, Mari Davide, Bisonni Renato, Giordani Paolo, Giustini Lucio, Lippe Paolo, Silva Rosarita, Mattioli Rodolfo, Torresi Umberto, Latini Luciano, Magnani Mauro
Abstract excerpt
BACKGROUND: Gastric cancer is the second highest cause of cancer mortality in the world, despite declining rates of incidence in many industrialized countries. We carried out a case-control study to evaluate whether polymorphisms of DNA repair and glutathione S-transferase (GST) genes modulate the risk of developing diffuse gastric cancer. METHODS: ERCC1 118 T/C, XRCC1 399 G/A, XPD 312 G/A, XPD 751 A/C, XRCC3 241...
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