Article
The role of gene-environment interaction in the aetiology of human cancer: examples from cancers of the large bowel, lung and breast.
Journal of internal medicine - 1 Jun 2001
Mucci L A, Wedren S, Tamimi R M, Trichopoulos D, Adami H O
Abstract excerpt
It has become increasingly clear that cancer can be considered neither purely genetic nor purely environmental. A relatively new area of cancer research has focused on the interaction between genes and environment in the same causal mechanism. Primary candidates for gene-environment interaction studies have been genes that encode enzymes involved in the metabolism of established cancer risk factors. There are...
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