Article
The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs.
Development (Cambridge, England) - 1 Sept 1990
Phillips R G, Roberts I J, Ingham P W, Whittle J R
Abstract excerpt
We demonstrate the role of the segment polarity gene patched (ptc) in patterning in the cuticle of the adult fly. Genetic mosaics of a lethal allele of patched show that the contribution of patched varies in a position-specific manner, defining three regions in the wing where ptc clones, respectively, behave as wild-type cells, affect vein formation, or are rarely recovered. Analysis of twin clones demonstrates...
Topics
- Alleles
- Animals
- Cell Communication
- Cell Differentiation
- Drosophila
- Microscopy, Electron
- Mosaicism
- Mutation
- Nucleic Acid Hybridization
- Transcription, Genetic
- Wings, Animal