Article
Unrestricted expression of the Drosophila gene patched allows a normal segment polarity.
Nature - 12 Sept 1991
Sampedro J, Guerrero I
Abstract excerpt
In the Drosophila embryo, mutations in the segment polarity gene patched (ptc) cause the replacement of the middle region of each segment by a mirror-image duplication of the remaining structures, including the parasegmental border. This gene, which encodes a transmembrane protein, is initially expressed in a generalized way at blastoderm, but later stops being transcribed in cells expressing the engrailed gene,...
Topics
- Animals
- Animals, Genetically Modified
- Drosophila Proteins
- Drosophila melanogaster
- Gene Expression
- Insect Hormones
- Membrane Proteins
- Morphogenesis
- Phenotype
- Receptors, Cell Surface
- Transcription, Genetic