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Article

patched overexpression causes loss of wingless expression in Drosophila embryos.

Developmental biology - 1 Jul 1994

Schuske K, Hooper J E, Scott M P

Abstract excerpt

The patched (ptc) segment polarity gene of Drosophila encodes a transmembrane protein involved in cell signaling that establishes pattern within the segment. In the posterior half of the parasegment Patched protein represses transcription of the wingless (wg) gene by an unknown mechanism. In the most posterior row of cells in each parasegment this repression is neutralized by a signal possibly carried by the...

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Identifiers

PMID: 8026632
DOI: 10.1006/dbio.1994.1200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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patched overexpression causes loss of wingless expression in Drosophila embryos.PMID 8026632Read ↗

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The consequences of ubiquitous expression of the wingless gene in the Drosophila embryo.Semantic proximity Read ↗

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The patched signaling pathway mediates repression of gooseberry allowing neuroblast specification by wingless during Drosophila neurogenesis.Semantic proximity Read ↗

Differential requirements for segment polarity genes in wingless signaling.Semantic proximity Read ↗

Hedgehog induces opposite changes in turnover and subcellular localization of patched and smoothened.Semantic proximity Read ↗

Drawing a stripe in Drosophila imaginal disks: negative regulation of decapentaplegic and patched expression by engrailed.Semantic proximity Read ↗

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