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Article

The Relationships of Obesity-Related Genetic Variants With Metabolic Profiles and Response to Metformin in Clozapine-Treated Patients With Schizophrenia.

Journal of clinical psychopharmacology - 1 Oct 2015

Chen Po-Yu, Lu Mong-Liang, Huang Ming-Chyi, Kao Chung-Feng, Kuo Po-Hsiu, Chiu Chih-Chiang, Lin Shih-Ku, Chen Chun-Hsin

Abstract excerpt

Obesity-related genetic variants, including TMEM18 (rs6548238), SH2B1 (rs7498665), and GNPDA2 (rs10938397), have been shown to be associated with obesity in the general population. Our study aimed to test whether these genetic variants are associated with metabolic profiles and metformin treatment response in clozapine-treated schizophrenic patients. We recruited 107 clozapine-treated patients who were genotyped...

Read the complete abstract on PubMed

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Share to Adaptor Proteins, Signal Transducing
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Source

Identifiers

PMID: 26263223
DOI: 10.1097/JCP.0000000000000386

Genes

TMEM18
GNPDA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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