Article
Six novel single nucleotide polymorphisms of the steroid sulfatase gene in a Japanese population.
Drug metabolism and pharmacokinetics - 1 Jan 2010
Matsumoto Jun, Ariyoshi Noritaka, Ishii Itsuko, Kitada Mitsukazu
Abstract excerpt
Steroid sulfatase (STS) is a microsomal enzyme responsible for the formation of 3beta-hydroxysteroid from the corresponding sulfate conjugates. Screening of all exons, exon-intron boundaries and the 5'-flanking region of the STS gene in 93 healthy Japanese individuals was carried out. Among seven single nucleotide polymorphisms (SNPs) identified in this study, six were novel, including one in the untranslated...
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