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Article

Brief review of polymorphic drug-metabolizing enzymes in Japanese populations: development of a higher-throughput genotyping method and proposed applications.

Drug metabolism letters - 1 Apr 2007

Kubota Takahiro

Abstract excerpt

Different functional alleles for each subtype of cytochrome P450 (CYPs), thiopurine S-methyltransferase (TPMT), glutathione S-transferase (GST) and sulfotransferase (SULT) enzymes, have been identified. In this review, the genetic polymorphisms of drug-metabolizing enzymes in the Japanese population and their effects on metabolic activity are described in detail.

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Identifiers

PMID: 19356033
DOI: 10.2174/187231207780363679

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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