Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization.

doi:10.1111/j.1365-2141.2010.08341.x

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Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization.

British journal of haematology - 1 Nov 2010

Setlur Sunita R, Ihm Chunhwa, Tchinda Joelle, Shams Soheil, Werner Lillian, Cho Eun Kyung, Thompson Christina, Phillips Kimberly, Rassenti Laura Z, Kipps Thomas J, Neuberg Donna, Freedman Arnold S, Lee Charles, Brown Jennifer R

Abstract excerpt

Approximately 10% of patients with chronic lymphocytic leukaemia (CLL) have a family history of the disease or a related lymphoproliferative disorder, yet the relationship of familial CLL to genomic abnormalities has not been characterized in detail. We therefore studied 75 CLL patients, half familial and half sporadic, using high-resolution array comparative genomic hybridization (CGH), in order to better define...

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Comparison of familial and sporadic chronic lymphocytic leukaemia using high resolution array comparative genomic hybridization.

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