Article
Familial chronic lymphocytic leukemia.
Current hematologic malignancy reports - 1 Oct 2008
Houlston Richard S, Catovsky Daniel
Abstract excerpt
The role of inherited genetic factors in the etiology of chronic lymphocytic leukemia (CLL) and other B-cell lymphoproliferative disorders is now well established. Significant familial aggregation of CLL and B-cell lymphoproliferative disorders has been demonstrated, but the mode of inheritance is unknown. Identification of genes that when mutated confer an increased risk of these diseases is of immediate...
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