Article
A genome scan of 18 families with chronic lymphocytic leukaemia.
British journal of haematology - 1 Jun 2003
Goldin Lynn R, Ishibe Naoko, Sgambati Maria, Marti Gerald E, Fontaine Laura, Lee Maxwell P, Kelley Jenny M, Scherpbier Titia, Buetow Kenneth H, Caporaso Neil E
Abstract excerpt
Chronic lymphocytic leukaemia (CLL) accounts for about 30% of all leukaemias and is most prevalent in older individuals. Significant familial aggregation has been demonstrated but the mode of inheritance is unknown. Recurrent cytogenetic abnormalities are frequently found in CLL tumour cells but no susceptibility genes have been confirmed. We have collected clinical data and biospecimens on families ascertained...
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