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Article

Identification of a novel chromosome region, 13q21.33-q22.2, for susceptibility genes in familial chronic lymphocytic leukemia.

Blood - 1 Feb 2007

Ng David, Toure Ousmane, Wei Ming-Hui, Arthur Diane C, Abbasi Fatima, Fontaine Laura, Marti Gerald E, Fraumeni Joseph F, Goldin Lynn R, Caporaso Neil, Toro Jorge R

Abstract excerpt

Chronic lymphocytic leukemia (CLL) is the most prevalent form of leukemia in adults in western countries. A genome scan of CLL-prone families revealed a lod score of one in band 13q22.1. To investigate this finding, we selected 6 CLL families consisting of 63 individuals (CLL affected, n=19; unaffected, n=44) for fine mapping of a 23-megabase region in 13q14.2-q22.2. Interphase fluorescence in situ hybridization...

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Identifiers

PMID: 17047154
DOI: 10.1182/blood-2006-03-011825

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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