Article
Chromosomal imbalances in familial chronic lymphocytic leukaemia: a comparative genomic hybridisation analysis.
Leukemia - 1 Jul 2002
Summersgill B, Thornton P, Atkinson S, Matutes E, Shipley J, Catovsky D, Houlston R S, Yuille M R
Abstract excerpt
A subset of B cell chronic lymphocytic leukaemia (CLL) is familial. Lack of large families makes it attractive to exploit methods in addition to genetic linkage analysis for the identification of a susceptibility locus. One strategy that can localise regions of the genome that may harbour tumour suppressor genes is to identify regions of chromosomal imbalance using comparative genomic hybridisation (CGH)...
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