Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bacterial charity work leads to population-wide resistance.

Nature - 2 Sept 2010

Lee Henry H, Molla Michael N, Cantor Charles R, Collins James J

Abstract excerpt

Bacteria show remarkable adaptability in the face of antibiotic therapeutics. Resistance alleles in drug target-specific sites and general stress responses have been identified in individual end-point isolates. Less is known, however, about the population dynamics during the development of antibiotic-resistant strains. Here we follow a continuous culture of Escherichia coli facing increasing levels of antibiotic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Drug Resistance, Bacterial
Share to Gene Expression Profiling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome, Bacterial

Share to Indoles

Share to Microbial Sensitivity Tests

Share to Microbial Viability

Share to Norfloxacin

Source

Open in PubMed Open full text

Identifiers

PMID: 20811456
DOI: 10.1038/nature09354
PMCID: PMC2936489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bacterial charity work leads to population-wide resistance.PMID 20811456Read ↗

Determinants of Genetic Diversity of Spontaneous Drug Resistance in Bacteria.Semantic proximity Read ↗

Phenotypic resistant single-cell characteristics under recurring ampicillin antibiotic exposure in Escherichia coli.Semantic proximity Read ↗

Higher levels of antibiotic resistance are less competitive: the hidden ecological cost of no-metabolic cost resistanceSemantic proximity Read ↗

Antibiotic resistant bacteria survive treatment by doubling while shrinking.Semantic proximity Read ↗

Efflux-linked Accelerated Evolution of Antibiotic Resistance at a Population EdgeSemantic proximity Read ↗

Cryptic Evolution of Heteroresistance as Adaptation to Treatment InterruptionsSemantic proximity Read ↗

Bacterial heteroresistance mechanisms, dynamics, and emerging diagnostic approaches.Semantic proximity Read ↗

Efflux pump activity potentiates the evolution of antibiotic resistance across S. aureus isolates.Semantic proximity Read ↗

Community interactions drive the evolution of antibiotic tolerance in bacteria.Semantic proximity Read ↗

A genome-wide atlas of antibiotic susceptibility targets and pathways to toleranceSemantic proximity Read ↗

Fitness Costs of Antibiotic Resistance Impede the Evolution of Resistance to Other Antibiotics.Semantic proximity Read ↗

Idiosyncratic fitness costs of ampicillin-resistant mutants derived from a long-term experiment with <i>Escherichia coli</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.